In the latest talk @User spoke about strive, and being able to connect the cpu to memory blocks. Can openlane handle multiple blocks now?

It could always handle multiple block, but it simply requires using a special interactive script for full control on your macros and their positioning. Check what @Praharsha managed (you can find her messages and link to the repo she worked on on this channel).

@Matt Venn: I ran the flow on an analog macro. You can check our the details here: https://github.com/praharshapm/vsdmixedsignalflow