My understanding (which could always be incorrect) is that SkyWater just prepares the wafers as usual (with their own overglass cut at the end), but that Micross makes no assumptions and will etch over the pads regardless.
We had a three-way negotiation between SkyWater, Micross, and efabless as to where to put those alignment markers, and settled on the corner of the two test die areas as the best place. I generated the redistribution layout for the Caravel padframe, and then we arrayed those into a full reticle and dropped the two alignment markers at the agreed-upon spot. Looks like that all worked perfectly!